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. Author manuscript; available in PMC: 2021 Jul 9.
Published in final edited form as: ACS Appl Bio Mater. 2020 Dec 24;4(1):229–251. doi: 10.1021/acsabm.0c01145

Figure 4.

Figure 4.

Brain tissue slices for (A) untreated rats and rats treated with (B) naked siRaf-1, (C) CPT-loaded MPEG-PCL-Tat/siControl, (D) MPEG-PCL-Tat/siRaf-1, and (E) CPT-loaded MPEG-PCL-Tat/siRaf-1. The greatest reduction in tumor size was seen with the peptide modified polymer micelle loaded with both drug and gene therapeutics. Reprinted with permission from reference.142 Copyright 2014 American Chemical Society.