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. 2021 Jul 2;22(13):7176. doi: 10.3390/ijms22137176

Figure 4.

Figure 4

Unique upregulation profiles for genes encoding for members of the Rho-GTPase GAP and GEF families of proteins. Transcriptome data showing the temporal expressions of 8 of the 23 Arhgap genes and 7 of the 17 Arhgef genes upregulated in the salivary glands of C57BL/6.NOD-Aec1Aec2 mice (lower panels). In each case, upregulated expressions started around 8 weeks of age. In contrast, expressions of these Arhgap and Arhgef genes remain downregulated.