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. 2021 Jul 1;22(13):7149. doi: 10.3390/ijms22137149

Table 2.

Critical appraisal of nonrandomized studies.

Lead Author (Year) Level of Evidence MINORS Score a
Fickert (2012) [15] 2b 11
Siebold (2014) [16] 4 9
Siebold (2016) [17] 4 8
Siebold (2018) [18] 4 12
Hoburg (2019) [19] 3b 19 *
Grevenstein (2020) [20] 4 8
Niemeyer (2020) [21] 2b 22 *
Sumida (2021) [22] 3b 8

a Methodological Index for Nonrandomized Studies (MINORS) scores were out of a possible ideal of 16 for noncomparative studies and 24 for comparative studies (*). The levels of evidence are explained in the legend of Table 1.