Table 3.
Univariable and multivariable binary logistic regression analysis of factor associated with abnormal. Cardiac index reserve.
| Univariable Analysis | Multivariable Model | |||
|---|---|---|---|---|
| OVERALL (n = 1344) | ||||
| Variables | OR (95%CI) | p | OR (95%CI) | p |
| Female Sex | 1.329 (1.056–1.672) | 0.015 | 1.819 (1.372–2.413) | <0.001 |
| Age | 1.035 (1.024–1.046) | <0.001 | 1.027 (1.013–1.040) | <0.001 |
| Hypertension (yes) | 1.609 (1.250–2.070) | <0.001 | ||
| Diabetes (yes) | 1.666 (1.257–2.208) | <0.001 | ||
| Rest WMSI | 0.984 (0.642–1.509) | 0.942 | ||
| Rest Ejection Fraction % | 1.009 (0.995–1.024) | 0.205 | ||
| Peak Ejection Fraction % | 0.951 (0.940–0.962) | <0.001 | 0.932 (0.916–0.948) | <0.001 |
| Inability to perform 85% age-predicted HR | 2.752 (2.177–3.749) | <0.001 | 2.363 (1.177–3.140) | <0.001 |
| Blunted LVCR (peak FORCE/rest FORCE ≤ 2) | 1.246 (0.992–1.565) | 0.059 | 1.579 (1.105–2.259) | 0.012 |
| Chronotropic incompetence (stress/rest HR < 1.85) | 3.636 (2.860–4.623) | <0.001 | 3.923 (2.915–5.279) | <0.001 |
| Reduced preload reserve (peak EDV < rest EDV) | 2.928 (2.272–3.773) | <0.001 | 5.610 (4.025–7.821) | <0.001 |
Lower tertile, ≤1591 mL/min × m−2 Cardiac index increase. CI, confidence intervals; HR, heart rate; OR, odds ratio; WMSI, wall motion score index.