Table 1.

Regulation of NM II. Several kinases regulate the activation/inactivation state of NM II through the phosphorylation of different Ser and Thr residues. Myosin light chain kinase (MLCK), Rho-associated protein kinase (ROCK), citron Rho-interacting kinase (CRIK), death-associated protein kinase (DAPK3), myotonic dystrophy-related Cdc42-binding protein kinase (MRCK), leucine-zipper-interacting kinase (ZIPK), p-21 activated kinase (PAK), casein kinase II (CKII), protein kinase C (PKC).

Effect on NM II.	Kinases	References
Activation at Thr18 and Ser19	MLCK	[39]
	ROCK	[39]
	CRIK	[32]
	DAPK3	[33]
	MRCK	[38]
	ZIPK	[33]
Activation at Ser19	PAK	[35]
Activation at Ser1943	CKII	[21,52]
Activation at Ser1916 and Ser1937	PKC	[21,52,53]
Inactivation at Thr9, Ser1 and Ser2	PKC	[21,54]