Table A1.
Evaluation of the structural quality of the modeled structures.
| Quality Parameters | Membrane Protease | SRBD | Nsp14 | TMPRSS2 |
|---|---|---|---|---|
| Template | 6VXX | 7KJR.A | 5C8S.B | 7MEQ.1.A |
| RMSD (Å) from template | 0.6 | 0.8 | 0.8 | |
| QMEAN | −5.68 | −1.12 | −2.15 | −0.51 |
| GMQE | 0.19 | 0.88 | 0.93 | 0.53 |
| MolProbity score | 2.21 | 0.72 | 2.59 | 1.24 |
| Ramachandran favoured (%) | 92.93 | 96.59 | 95.98 | 95.03 |
| Ramachandran outliers (%) | 2.02 | 0.00 | 0.38 | 0.29 |
| Rotamer outliers (%) | 0.00 | 0.00 | 15.87 | 0.68 |
| Bad bonds | 0/808 | 1/1454 | 3/4338 | 0/2766 |
| Bad angles | 17/1094 | 7/1981 | 69/5900 | 20/3766 |
Notes: Nsp14-non-structural protein 14; SRBD-spike receptor binding domain; TMPRSS2-transmembrane protease, serine 2.