Table 9.
Case reports regarding treatment of craniofacial defects and diseases using MSCs.
| Type of Study | Stem Cell Source (n) | Outcome | Reference |
|---|---|---|---|
| Case report | AdSCs with fibrin glue | Good ossification and reconstruction of bone defect | [194] |
| Case report | AdSCs | Being a safe procedure allowing rapid organotypic recovery of the lost tissue | [195] |
| Case report | AdSCs in combination with TCP and BMP-2 | Expression of osteogenic-related markers, including OC, OP, ColI, and RUNX-2, reconstruction of bone defect | [196] |
| Case report | AdSCs seeded on bioscaffolds in combination with BMP-2 | Reconstruction of craniofacial osseous defects | [197] |
| Case report | AdSCs | Successful integration to the mandibular symphysis with bone defect | [198] |
| Case report | AdSCs | Reconstruction of the mandibular ameloblastoma defects | [199] |
| Case report | Combination of AdSCs with four different scaffolds | Reconstruction of complex mandibular defects | [200] |
| Case report | AdSCs seeded on Coll/Pro Osteon 200 scaffold | Bone regrowth and skeletal development in zygomatic and maxillary defects | [201] |
| Case report | BMSCs seeded onto b-TCP | Successful upper jaw reconstruction | [202] |
BMSCs: Bone marrow-derived stem cells. AdSCs: Adipose tissue-derived stem cells. Coll/Pro Osteon 200: Hydroxylapatite-collagen hybrid 200. b-TCP: b-tricalcium phosphate. OP: Osteopontin. OC: Osteocalcin. BMP: Bone morphogenetic proteins.