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ATC and PDTC genetic landscape: gene fusions.
| Gene Fusions | Mutation Rate [16,18,29,44,46] |
||
|---|---|---|---|
| ATC | PDTC | ||
| PAX8-PPARγ Fusions | 0 | 3/84 | |
| NTRK fusions | NTRK1-IRF2BP2 | 1/126 | 0 |
| NTRK2-CRNDE | 1/126 | 0 | |
| ETV6-NTRK3 | 0 | 1/60 | |
| RET fusions | CCDC6-RET | 2/126 | 3/84, 2/60 |
| NCOA4-RET | Case report | 2/84, 1/23 | |
| PDCD10-RET | 0 | 1/60 | |
| TFG-RET | 0 | 1/60 | |
| ALK fusions | STRN-ALK | Case report | 1/23 |
| EML4-ALK | 0 | 2/84 | |
| BRAF fusions | KIAA1549-BRAF | Case report | 0 |
| SCRIB-BRAF | 0 | 1/60 | |
| Other fusions | NUT-BRD4 | 1/33 | 0 |
