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. 2021 Jun 25;13(13):3175. doi: 10.3390/cancers13133175

Table 4.

The associations between the expression levels of the BCL2 family genes and other factors, detected by MANOVA, in the studied AML patients. * p < 0.05, ** p < 0.01, *** p < 0.001.

Expression of Genes Associated Factor p Value
BCL2L1, BID, BOK, HRK BRCA2_status, RUNX1_status 4.145 × 10−10 ***
0.04287 *
BCL2L1, BID, BOK, HRK BRCA2 status 2.106 × 10−9 ***
BCL2L1, BID, HRK RUNX1 status 0.0002187 ***
BCL2L10, BCL2L2, HRK HNRNPU status 8.038 × 10−7 ***
BCL2L1, BBC3, BOK, BCL2L10, BCL2L11 HNRNPH2 status 1.129 × 10−5 ***
BCL2L11, BCL2L13, BID, BIK, BNIP1 WBC count 6.459 × 10−5 ***
HRK, BAK1, BCL2A1, BID, BNIP1 SNRNP200 status 0.002168 **
BCL2L10, BNIP2 DDX42 status 0.000545 ***
BCL2, BCL2A1, BCL2L10, BID, BNIP1, MCL1 CWC27 status 0.007744 **
BMF, RTL10, BAX, BCL2L11, BCL2L2 CEBPA status 0.00383 **
BCL2L13, BIK, PMAIP1 RBMX status 0.0004931 ***
MCL1, BCL2L11 HNRNPUL1 status 0.05703
BCL2L2.PABPN1, BNIP2 DHX38 status 0.009772 **
BCL2, BCL2L11, BCL2L12, BCL2L15 EP300 status 0.04793 *
BCL2L13, BCL2L2, BIK ATM status 0.003997 **
BAX, BCL2A1, BNIP2 KRAS status 0.01254 *
BCL2L13, BCL2L2 DNMT3A status 0.02401 *
BNIP1, BCL2L2.PABPN1 IDH1 status 0.01978 *
BBC3, BCL2L1, BCL2L11, BOK, MCL1 IDH2 status 0.02641 *
BCL2L1, BOK IDH2 status,
MCL1 status
0.001286 **
0.007325 **
BCL2L1, BOK IDH2 status,
MCL1 status,
BRCA2 status
1.755 × 10−5 ***
4.508 × 10−5 ***
4.624 × 10−6 ***
BCL2L1, BOK MCL1 status 0.001242 **
BAD, BAK1, BCL2L11, BID, BNIP2, BNIP3 RUNX1-RUNX1T1 status 0.002101 **
BCL2L13, BID, BIK, BNIP1 NPM1 status 0.02555 *
BAD, BAX, BCL2L1, BCL2L11, BCL2L13, BCL2L2.PABPN1, BID, BIK, BNIP1, BOK Blast percentage in PB 0.003099 **
BCL2L1, BCL2L11, BCL2L15, BCL2L2.PABPN1, BID, BIK, BNIP1, BOK, HRK Blast percentage in BM 0.000261 ***
BAK1, BBC3, BCL2L1, BCL2L11, BCL2L12, BOK Tissue type (PB, BM) 0.0004833 ***
BCL2L15, BCL2L2, BNIP1, BNIP3 FAB type (M1, M2) 0.03326 *