APCs |
Antigen-presenting cells |
ATP |
Adenosine triphosphate |
CD4 |
Cluster of differentiation 4 |
CD8 |
Cluster of differentiation 8 |
CD28 |
Cluster of Differentiation 28 |
CD 40 |
Cluster of differentiation 40 |
CD48 |
Cluster of Differentiation 48 (B-lymphocyte activation marker) |
CD68 |
Cluster of Differentiation 68 |
CD 80 |
Cluster of differentiation 80 |
CRP |
C-reactive protein |
CT |
Computed Tomography |
CTLA-4 |
Cytotoxic T-lymphocyte antigen 4, CD152 |
DAMPs |
Damage-associated molecular patterns |
DAB |
3:3′-Diaminobenzidine |
DCs |
Dendritic Cells |
Gy |
Gray (unit) |
H&E |
Hematoxylin eosin staining |
HMGB1 |
HMGB1 |
HRP |
horseradish peroxidase |
ICAM1 |
Intercellular Adhesion Molecule 1 |
ICD |
Immunogenic cell death |
IFNs |
Interferons |
IFN-γ: |
Interferon gamma |
IL |
Interleukin |
IL-1β |
Interleukin 1 beta |
IL-18 |
Interleukin 18 |
IL-2: |
Interleukin 2 |
IL-6: |
Interleukin 6 |
IL-12β: |
Interleukin 12 beta |
IPRES |
Innate PD-1 RESistance |
LDH |
Lactate dehydrogenase |
MHC |
Major histocompatibility complex |
NK |
Natural killer cell |
NRL |
Neutrophil to lymphocyte ratio |
ORR |
Objective response rate |
OS |
Overall survival |
P2 × 7 |
P2X purinoceptor 7 |
PBS |
Phosphate-buffered saline |
PD-1 |
Programed cell death 1, CD279 |
PFS |
Progression free survival |
SD |
Stable disease |
S100B |
S100 calcium-binding protein B |
TAMs |
Tumor-associated macrophages |
TILs |
Tumor-infiltrating lymphocytes |
TNF-α. |
Tumor necrosis factor alfa |
VCAM1 |
Vascular cell adhesion protein 1 |