Table 5.
Identified HPV type in a histological tissue of VaIN, VaSCC and CIN.
| HPV Type | VaIN1 | VaIN2/3 | VaSCC | Total | CIN1 | CIN2/3 | Total | ||
|---|---|---|---|---|---|---|---|---|---|
| N = 49 * | N = 17 | p | N = 7 | No. | N = 10 | N = 16 | No. | ||
| High-risk HPV | HPV16 | 1 | 6 | 1 | 8 | 2 | 2 | ||
| HPV18 | 1 | 1 | 1 | 1 | |||||
| HPV31 | 1 | 1 | |||||||
| HPV39 | 2 | 2 | |||||||
| HPV45 | 1 | 1 | |||||||
| HPV51 | 2 | 2 | 3 | 3 | |||||
| HPV52 | 1 | 2 | 3 | 1 | 6 | 7 | |||
| HPV56 | 1 | 1 | 2 | ||||||
| HPV58 | 1 | 2 | 1 | 4 | 1 | 1 | |||
| HPV68 | 1 | 1 | 2 | 2 | 2 | ||||
| Possibly high-risk HPV | HPV34 | 3 | 3 | ||||||
| HPV53 | 6 | 1 | 7 | 1 | 1 | ||||
| HPV66 | 5 | 1 | 6 | 1 | 1 | 2 | |||
| HPV67 | 3 | 1 | 4 | 2 | 2 | ||||
| HPV73 | 1 | 1 | |||||||
| Low-risk HPV | HPV42 | 2 | 2 | 4 | |||||
| HPV61 | 2 | 2 | |||||||
| HPV71 | 3 | 3 | |||||||
| HPV81 | 5 | 5 | |||||||
| HPV84 | 2 | 2 | 1 | 1 | |||||
| HPV90 | 5 | 5 | 1 | 1 | |||||
| Negative | 6 | 0 | 1 | 7 | 1 | 0 | 1 | ||
| Any HPV type | 43 (87.8%) | 17 (100%) | 6 (85.7%) | 66 (90.4%) | 9 (90.0%) | 16 (100%) | 25 (96.1%) | ||
| HR-HPV type | 6 | 14 | <0.001 | 4 | 24 | 3 | 15 | 18 | |
| Possibly HR-HPV type | 18 | 1 | 0.015 | 2 | 21 | 4 | 1 | 5 | |
| LR-HPV type | 19 | 2 | 0.084 | 0 | 21 | 2 | 0 | 2 | |
| Total | 49 | 17 | 7 | 73 | 10 | 16 | 26 | ||
*: N means the number of the tissue specimens, CIN, cervical intraepithelial neoplasia; HPV, Human papillomavirus; HR-HPV, High risk-HPV; LR-HPV, Low risk-HPV; N, number; VaSCC, vaginal squamous cell carcinoma; VaIN, vaginal intraepithelial neoplasia. p value means comparing the prevalence of HPV infection between VaIN1 and VaIN2/3 cases.