Fig. 1.

Association of the nucleoside/nucleotide reverse transcriptase inhibitors (N(t)RTI) backbone with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seropositivity by logistic regression analysis. Multivariable models were adjusted by sex, age, country of birth, education level, comorbidities, route of HIV acquisition, prior AIDS, CD4+ cell count, HIV viral load, type of third antiretroviral drug used, and month of sample collection. To avoid sparse data bias, we used penalization through data augmentation to perform multivariate logistic regression. TAF, tenofovir alafenamide; FTC, emtricitabine; TDF, tenofovir disoproxil fumarate; ABC, abacavir; 3TC, lamivudine; ART, antiretroviral therapy; OR, odds ratio; CI, confidence interval.