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. 2021 Jun 25;9:707319. doi: 10.3389/fbioe.2021.707319

FIGURE 10.

FIGURE 10

Schematic illustration of NIR light/pH/reduction-responsive nanoparticles. The NIR Light/pH/Reduction–responsive nanoparticles consist of PEG-a-PCL-SSP(NIPAM-co-DMA) (S1) star quaterpolymer for precise cancer therapy synergistic effects. Reprinted from Xiaonan An, Aijun Zhu, Huanhuan Luo, et al. Rational Design of Multi-Stimuli-Responsive Nanoparticles Precise Cancer Therapy. ACS Nano. 2016;10(6):5947–58. With permission from reference (An et al., 2016). NIR, near-infrared; PEG, poly(ethylene glycol); PCL, poly(ε-caprolactone); NIPAM, N-isopropylacrylamide; DMA, dimethylacrylamide; GSH, cytoplasmic glutathione; MS-NPs, multi-stimuliresponsive nanoparticles.