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. 2021 Jun 25;9:707319. doi: 10.3389/fbioe.2021.707319

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Copyright © 2021 Chang, Ma, Xu, Xie and Ju.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic illustration of the magnetic field-responsive polymer micelles. Schematic chemical structure (A) and molecular architecture (B) of clickable multiblock polyurethanes (MPUs). (C) Self-assembly of MPU micelles and post-conjugation of folic acid via click chemistry. (D) Schematic illustration of FA residues on the interface of polymer micelles. (E) Illustration of magnetic-guided and PEG-switched targeting and release properties of MPU nanocarriers. Reprinted from Jing Wei, Xiaoyu Shuai, Rui Wang, et al. Clickable and imageable multiblock polymer micelles with magnetically guided and PEG-switched targeting and release property for precise tumor theranostics. Biomaterials. 2017;145:138–53. With permission from reference (Wei et al., 2017).