Table 7.
Type of Polymeric DDS | [CUR] Formulation | Microorganism | Type of Culture | Antimicrobial Method | Antimicrobial [CUR] | Light/Ultrasonic Parameters | Reference |
---|---|---|---|---|---|---|---|
PEG 400 γ-CD and PEG + β-CD |
0.18% |
E. faecalis
E. coli |
Planktonic | CFU/mL aPDT |
N/R | 9.7 J/cm2 29 J/cm2 |
[158] |
CUR-NP without polymer | 100 mg |
S. aureus
B. subtillis E. coli P. aeruginosa P. notatum A. niger |
Planktonic | MIC Inhibition zone |
100 mg 0.27 mmol |
- | [159] |
CUR-NP without polymer | 100 mg |
M. lutues
S. aureus E. coli P. aeruginosa |
Planktonic | MBC | N/R | - | [160] |
Mixed polymer NP | 5 mM | E. coli | Planktonic | MIC | 400–500 μM | - | [161] |
CTAB Tween 20 Sodium dodecylsulfate |
100 mg/mL | L. monicytogenes | Planktonic | Inhibition zone | N/R | - | [162] |
PLA/dextran sulfate | 4 mg/mL | MRSA C. albicans S. mutans |
Planktonic/mono- and –mixed biofilm | aPDT | 260 μM | 43.2 J/cm2 | [163] |
PLA/dextran sulfate | 0.4% | C. albicans | Animal model | aPDT | 260 μM | 37.5 J/cm2 | [164] |
Nanocurcumin | N/R | P. aeruginosa (isolates) and standard strain | Planktonic | MIC | 128 µg/mL | - | [165] |
PLGA | 5 mg |
S. saprophyticus subsp. Bovis E. coli |
Planktonic | aPDT | 50 µg/mL | 13.2 J/cm2 | [166] |
Eudragit L-100 | N/C | L. monocytogenes | Planktonic | Animal model infection | N/R | - | [167] |
nCUR | N/R | S. mutans | Planktonic Biofilm |
Inhibition zone aPDT |
N/R | 300–420 J/cm2 | [168] |
nCUR combined with indocyanine | 100 mg | E. faecalis | Biofilm | Metabolic activity | N/R | 500 mW/cm2 | [169] |
PVAc-CUR-PET-PVDC | 0.02 g |
S. aureus
S. tiphimurium |
Planktonic | aPDT | N/R | 24, 48, and 72 J/cm2 | [170] |
MOA.CUR-PLGA-NP | Up to 10% | S. mutans | Biofilm | aPDT | 7% wt | 45 J/cm2 | [171] |
CS- β-CD | N/C |
S. aureus
E. coli |
Planktonic | Colony count | Up to 0.03% | - | [172] |
[CUR]: CUR concentration. -: not performed. N/R: not reported. N/C: not clear.