Reduced placental OGT in female offspring on normal chow had an increase in fasting BG. (A) Non-fasted insulin at 12 weeks of normal chow for male mice (n = 5, 7). (A’) Non-fasted insulin of female mice at 12 weeks of NC (n = 3, 9). (B) IPGTT and (C) calculated AUC for male (n = 12) and (B’,C’) female mice (n = 12, 22) at 6 weeks on normal chow. (D) ITT at 8 weeks on normal chow for male (n = 13, 14) and (D’) females (n = 12, 18). Blood glucose values post insulin injection are expressed as a percent of baseline blood glucose. (A,C) were presented as mean ± SEM, unpaired t-test for males and one-way ANOVA for females. (B,D) were presented as mean ± SEM, two-way ANOVA. p values, * p < 0.05.