TABLE 2.
Drug characteristics and minimum inhibitory concentrations.
| Drug | Chemical formula | Mw (g mol–1) | MIC (μg ml–1) | Log P | Lag phase, tpen (h) | Water solubility (mg ml–1) |
| Nitrofurantoin | C8H6N4O5 | 238.16 | 4 | −0.47 | <1 | 0.08 |
| Nitrofurazone | C6H6N4O4 | 198.14 | 8 | 0.23 | <1 | 0.21 |
| Sparfloxacin | C19H22F2N4O3 | 392.4 | <0.016 | 2.5 | 4 < tpen < 24 | 0.11 |
| Chlorhexidine | C22H30Cl2N10 | 505.4 | >64 | 0.08 | 4 < tpen < 24 | 0.80 |
Minimum inhibitory concentration (MIC) is measured for uropathogenic Escherichia coli, UTI89. tpen = time to penetration (lag phase).