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. 2021 Jun 25;9:678967. doi: 10.3389/fcell.2021.678967

FIGURE 1.

FIGURE 1

SMARCC1 is downregulated in PCa tissues and correlates with poor prognosis. (A) Representative images of BPH and PCa tissues with Gleason score 7, 8, and 9 showing in situ SMARCC1 expression (magnification, ×100). (B) Disease-free survival of PCa patients with a different SMARCC1 expression from the GEPIA database. (C) Endogenous expression of SMARCC1 mRNA in immortalized normal prostatic epithelial cells and PCa cell lines. (D,E) SMARCC1 mRNA (D) and protein (E) levels in PCa cells transduced with SMARCC1 shRNA lentivirus. Relative mRNA expression levels are shown in the bar graph, and gray density values of proteins are indicated under the corresponding bands. All data are presented as mean ± SEM of at least three independent experiments. ***p < 0.001; ****p < 0.0001.