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. 2021 Jun 25;9:678967. doi: 10.3389/fcell.2021.678967

FIGURE 6.

FIGURE 6

PI3K/AKT pathway blockade reversed the phenotypic effect of SMARCC1 knockdown. (A) Viability rate, (B) number of colonies, (C) cell cycle distribution, and (D) Representative image of EdU for LNCAP with Sh-SMARCC1 was selected from area presented in Figure 2E for LNCAP cell line with Sh-SMARCC1. (E) Transwell assay on SMARCC1 knocked-down PCa cell lines treated with ly294002 (scale bar – 100 μm). (F) Wound healing assay on migration ability of SMARCC1 knocked-down PCa cell lines treated with ly294002. All data are presented as mean ± SEM of at least three independent experiments. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.