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. 2021 Jun 25;9:678967. doi: 10.3389/fcell.2021.678967

TABLE 2.

Correlation between SMARCC1 expression and pathological characteristics of PCa.

Pathological characteristics Immunohistochemical staining intensity
χ2 P-value
Low (n, %) Medium (n, %) Strong (n, %)
Age
≤60 4 (100) 2.664 0.264
>60 57 (59.4) 31 (32.3) 8 (8.3)
Gleason score
≤7 27 (50) 23 (42.6) 4 (7.4) 7.469 0.024
>7 34 (73.9) 8 (17.4) 4 (8.7)
T stage
T1–2 7 (46.7) 6 (40) 2 (13.3) 1.547 0.461
T3–4 50 (63.3) 23 (29.1) 6 (7.6)
Metastasis to lymph nodes
Yes 17 (73.9) 6 (26.1) 3.439 0.179
No 44 (57.1) 25 (32.5) 8 (10.4)
Invasion to seminal vesicle
Yes 37 (58.7) 21 (33.4) 5 (7.9) 0.375 0.829
No 21 (63.6) 9 (27.3) 3 (9.1)
AJCC clinicopathological stage
I–IIc 6 (50) 4 (33.3) 2 (16.7) 3.348 0.501
IIIa–IIIc 49 (60.5) 26 (32.1) 6 (7.4)
IVa–IVb 6 (85.7) 1 (14.3) 0
ERG staining
Negative 37 (63.8) 15 (25.9) 6 (10.3) 3.477 0.176
Positive 9 (42.9) 10 (47.6) 2 (9.5)

Bold values illustrate statistical significance.