2.

80株变异链球菌临床株中差异分布的sepM基因突变类型与变链素的关系

Association of the differentially distributed sepM mutations with mutacin Ⅳ production in the 80 clinical isolates of S. mutans

Mutation of base	Amino acid	Percentage of clinical isolates				Inhibition zone
		Mutacin Ⅳ group (%)	Mutacin Ⅳ-free group (%)	P		Mutation group (mm)	Control group (mm)	P
C31T	L	24.0	0	0.001		8.245±0.917	0.966±1.845	< 0.001
A165G	K	32.0	25.5	0.543		2.677±3.775	1.070±1.903	0.177
T232C	L	40.0	50.9	0.365		1.052±1.942	1.928±3.092	0.281
T366A	A	8.0	10.9	0.999		1.196±2.477	1.547±2.662	0.682
A429T	T	8.0	10.9	0.999		1.196±2.477	1.547±2.662	0.682
C432T	F	8.0	10.9	0.999		1.196±2.477	1.547±2.662	0.682
T438A	G	8.0	10.9	0.999		1.196±2.477	1.547±2.662	0.682
G533A	G178D	32.0	0	< 0.001		7.304±1.924	0.868±1.771	< 0.001
C588T	G	0	10.9	0.169		0	1.634±2.700	0.095
T634C	L	36.0	20.0	0.126		1.421±1.945	1.542±2.837	0.379
T726C	L	8.0	7.3	0.999		1.083±2.176	1.546±2.674	0.982
C756T	D	32.0	9.1	0.025		4.305±4.101	0.969±1.842	0.001
T768C	G	32.0	20.0	0.242		3.075±3.894	1.024±1.884	0.058
C831T	A	64.0	78.2	0.181		1.499±2.817	1.547±2.080	0.383
G843A	V	8.0	10.9	0.999		0.813±1.906	1.589±2.700	0.612
C908T	T303I	8.0	27.3	0.051		0.554±1.574	1.770±2.804	0.060
G954A	K	16.0	14.5	0.999		1.628±2.413	1.491±2.684	0.806
T963A	A	24.0	34.5	0.346		1.020±2.081	1.735±2.835	0.321
C1036T	H346Y	24.0	1.8	0.003		7.067±3.227	0.979±1.854	< 0.001