TABLE 1.

shRNA sequences have been previously published in The RNAi Consortium (TRC) and were purchased from Sigma-Aldrich cloned into pLKO.1 vector.

shRNA	TRC number	Sequence (5′–3′)
shNT	Nontarget	CAACAAGATGAAGAGCACCAA
shCD3γ-1	TRCN0000057223	CGGCTTCCTAACTGAAGATAA
shCD3γ-2	TRCN0000057224	CTGGCTATCATTCTTCTTCAA
shCD3γ-3	TRCN0000057225	CAGAACTGCATTGAACTAAAT
shCD3γ-4	TRCN0000057226	CCACCTTCAAGGAAACCAGTT
shCD3γ-5	TRCN0000057227	GTATTACAGAATGTGTCAGAA
shCD3δ-1	TRCN0000057218	GCATCCATTGAGATGATAATA
shCD3δ-2	TRCN0000057219	CCGTGCAAGTTCATTATCGAA
shCD3δ-3	TRCN0000057220	GAGGACAGAGTGTTTGTGAAT
shCD3δ-4	TRCN0000057221	GTTGAGGAATGACCAGGTCTA
shCD3δ-5	TRCN0000057222	CACTGCTCTCAGACATTACAA