Table 7.

Impact of TLR ligands on mouse infection rate as determined by cecal content ELISA and live ameba culture.

	LecA alone	LecA + GLA-3M-052 Liposomes ‘PP’	LecA + 3M-052 Liposomes	LecA + GLA Liposomes
% infected (culture)	65.2	21.7*,**	34.8	50.0
% infected (ELISA)	65.2	26.1*,**	34.8	45.8
# males infected (ELISA)	8 of 12	5 of 12	6 of 11	5 of 12
# females infected (ELISA)	7 of 11	1 of 11	2 of 12	6 of 12

LecA dose for all groups was 10 µg. *p < 0.05 by two-sided Fisher’s exact test without correction for multiple comparisons. **p < 0.05 by two-sided Fisher’s exact test with the Holm-Sidak correction for multiple comparisons.