Table 1.
Demographic data and C9orf72 hexanucleotide expansions in the cohort of 240 coronavirus disease 2019 (COVID-19) and 93 amyotrophic lateral sclerosis (ALS) patients.
| COVID-19 (n = 240) | ALS (n = 93) | p * | |
|---|---|---|---|
| Sex, female (%) | 147 (61.25 %) | 55 (59.13 %) | 0.125 |
| Mean age ± SD | 64.30 ± 12.18 | 64.74 ± 13.22 | 0.774 |
| Age range | 30–95 | 33–89 | |
| Caucasian ethnicity | 230 (95.83%) | 91 (97.85%) | 0.376 |
| Average number of repeats ± SD | 4.37 ± 3.15 | 4.61 ± 2.89 | 0.378 |
| Median number of repeats [interquartile range] |
2 [2–6] | 5 [2–7] | |
| Range | 2–18 | 2–19 | |
| Patients with >10 repeats (%) | 27 (11.25%) | 4 (4.30%) | 0.050 |
| Alleles with >10 repeats (%) | 27 (5.63%) | 4 (2.15%) | 0.056 |
SD: standard deviation. * Fisher’s exact test or Chi-square test for categorical variables and Student’s t-test for continuous variables were applied as appropriate.