Table 4.
Demographic data and C9orf72 hexanucleotide expansions in the validation cohort.
| MV/NIV (n = 101) |
Non-Hospitalized (n = 100) |
p * | |
|---|---|---|---|
| Sex, female (%) | 23 (22.77%) | 49 (49%) | 0.0001 |
| Mean age ± SD | 63.94 ± 9.07 | 51.97 ± 12.17 | 0.0001 |
| Age range | 33–86 | 18–81 | |
| Caucasian ethnicity | 97 (96.03%) | 100 (100%) | 0.1213 |
| Average number of repeats ± SD | 4.86 ± 3.64 | 4.47± 3 | 0.408 |
| Median number of repeats [interquartile range] |
3 [2–8] | 3 [2–6] | |
| Range | 2–19 | 2–20 | |
| Patients with >10 repeats (%) | 16 (15,84%) | 6 (6%) | 0.025 |
| Alleles with >10 repeats (%) | 16 (7.92%) | 6 (3%) | 0.030 |
SD: standard deviation. * Fisher’s exact test or Chi-square test for categorical variables and Student’s t-test for continuous variables were applied as appropriate.