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. 2021 Jul 2;13(13):3336. doi: 10.3390/cancers13133336

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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MRI with Gd-EOB-DTPA of a histologically confirmed combined hepatocellular cholangiocarcinoma located in the segment VI of the liver (arrow). The lesion presented without strong hyperintensity at the T2-weighted image (A) but showed hypointensity both in in- and out-of-phase T1-weighted images (B,C) and strong hyperintensity in the diffusion-weighted image (D). A strong hyperenhancement was evident during the arterial phase (E), followed by a persistent enhancement during the portal and late venous phases (F,G). In the hepatobiliary phase, the lesion appeared hypointense (H).