Table 2.

Select prebiotics target TLRs and proposed beneficial effects on intestinal tight junctions.

Prebiotic	Tight Junction Effects	Reference
Inulin	Increased occludin, claudin-3 and ZO-1 RNA expression	[102]
Fructo-oligosaccharide	ZO-1 and occludin apical redistribution	[104]
Galactooligosaccharide	Increased ZO-1, occludin and claudin-1 protein expression	[105,106]