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. 2021 Jun 23;13(13):3133. doi: 10.3390/cancers13133133

Table 1.

Summary of the main features of ultrasound-based thyroid nodule systems.

ACR-TIRADS Korean System UK BTA System
TR 1
0 points
Benign
K-TIRADS 1: no nodule U1: No nodule
TR 2
2 points
no suspicious
K-TIRADS 2: Benign U2: Benign
hyperechoic or isoechoic with a halo
cystic change with ring-down artifact (colloid)
  • microcystic or spongiform appearance

  • peripheral egg-shell calcification

  • peripheral vascularity

TR 3
3 points
Mildly suspicious
K-TIRADS 3: Low
partially cystic/isohyperechoic with
no suspicious features
U3: Indeterminate
solid homogenous markedly hyperechoic nodule with halo (follicular lesions)
  • hypoechoic with equivocal echogenic foci or cystic change

  • mixed or central vascularity

TR 4
TR4a = 4
TR4b = 5
TR4c = 6
from 4 to 6 points
Moderately suspicious
K-TIRADS 4: Intermediate
as for K-TIRADS 3 but with any
suspicious features or as for
K-TIRADS 5 without suspicious features
U4: Suspicious
solid hypoechoic (compared with thyroid)
  • solid very hypoechoic (compared with strap muscles)

  • hypoechoic with disrupted peripheral calcification

  • lobulated outline

TR 5 > 7 points
Highly suspicious
K-TIRADS 5: High
solid hypoechoic nodule with any suspicious feature
U5 Malignant
solid hypoechoic with a lobulated or irregular outline and microcalcification
  • papillary carcinoma

  • solid hypoechoic with a lobulated or irregular outline and globular calcification

  • medullary carcinoma

  • intranodular vascularity

  • taller than wide axially (AP > ML)

  • characteristic associated lymphadenopathy

American College of Radiology Thyroid Imaging, Reporting and Data System (ACR-TIRADS); K-TIRADS: Korean Tirads; UK BTA TIRADS: United Kingdom British Thyroid Association TIRADS. TR = TI-RADS; AP = anteroposterio; ML = mediolateral.