Table 1.
Major cholesterol efflux genes and their existing connection to lung cancer biology.
| Gene Symbol | Protein | Established Connection to Lung Cancer Biology in Literature |
|---|---|---|
| ABCA1 | ATP binding cassette A1 | Strong |
| Apo AI | Apolipoprotein AI | Strong |
| ABCG1 | ATP binding cassette G1 | Strong |
| miRNA-33 | Micro RNA-33 | Strong |
| LRP1 | LDL receptor related protein 1 | Strong |
| LIPA | Lysosomal acid lipase A | Weak |
| NPC1 | Niemann Pick Type C-1 | Weak |
| STARD3 | Steroidogenic acute regulatory D3 | Weak |
| SMPD1 | Sphingomyelinase phosphodiesterase 1 | Weak |
| NCEH1 | Neutral cholesteryl ester hydrolase | Weak |
| SR-BI | Scavenger Receptor BI | Weak |