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. 2021 Jul 1;22(13):7145. doi: 10.3390/ijms22137145

Figure 1.

Figure 1

Expression of ANO1 in the human keratinocyte HaCaT cell line and psoriatic tissue. (a) The expression of ANO1 mRNA and protein levels in HaCaT cells. (b) Expression of ANO1 protein in HaCaT cells using immunocytochemistry. Scale bar = 50 µm. (c) The expression of ANO1 protein in psoriatic skin tissue was increased compared to that of healthy skin tissue. Scale bar = 50 µm (insert: 20 µm). (d) Expression of ANO1 in the skin of normal and psoriasis from immunohistochemical analysis (ANO1 intensity of ten cells per unit area was measured using ZEN 3.1). To compare the differences of ANO1 expression between normal and psoriasis skin tissues, Student’s t-test was used. *: significantly different from normal skin (*** p < 0.001).