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. 2021 Jun 23;22(13):6760. doi: 10.3390/ijms22136760
∆LRRK2 ROC-COR-kinase plus the WD40 domain
AAV adeno-associated virus
ANOVA analysis of variance
CamKII calmodulin-kinase II
COR C-terminus of ROC
DA dopaminergic
DK double-mutant G2019S/D1994A dead kinase
GFP green fluorescent protein
GS G2019S mutation
HA hemagglutinin tag
K kinase domain of LRRK2
LB lysis buffer (50 mm Tris, pH 8.0, 150 mm NaCl, 1 mm EDTA, 0.5% Triton X-100, 1% NP40, protease inhibitors)
LRR leucin-rich repeats
LRRK2 leucin-rich repeats kinase 2
p-synS129 α-synuclein phosphorylated at serine 129
PBS phosphate-buffered saline
PBS-T phosphate-buffered saline with 0.2% Triton X-100
PD Parkinson’s disease
RCK kinase domain plus the ROC-COR domain
ROC Ras-of-complex protein
SNpc substantia nigra pars compacta
SNPs single-nucleotide polymorphisms
TH tyrosine hydroxylase
Vg viral particle
WT wild-type