Table 3.
Immunohistochemical comparisons.
| Parameter | CD8 | CD163 | MECA-79 | CD34 | PD-L1 Inflammatory Cells | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| High | Low | p | High | Low | p | High | Low | p | High | Low | p | Yes | No | p | |
| CD20 | |||||||||||||||
| High | 6 (8.3%) | 2 (2.7%) | 0.01 * | 3 (4.1%) | 5 (6.9%) | 0.8 | 2 (3.4%) | 6 (10.2%) | 0.07 | 4 (5.5%) | 4 (5.5%) | 0.9 | 2 (2.7%) | 6 (8.2%) | 0.9 |
| Low | 20 (27.4%) | 45 (61.6%) | 26 (35.6%) | 39 (53.4%) | 3 (5.1%) | 48 (81.3%) | 33 (45.2%) | 32 (43.8%) | 17 (23.3%) | 48 (65.8%) | |||||
| CD8 | |||||||||||||||
| High | 14 (18.9%) | 12 (16.2%) | 0.05 | 2 (3.4%) | 24 (40.7%) | 0.8 | 22 (29.7%) | 4 (5.4%) | <0.0001 § | 13 (16.1%) | 13 (16.1%) | 0.0007 £ | |||
| Low | 15 (20.3%) | 33 (44.6%) | 3 (5.1%) | 30 (50.8%) | 15 (20.3%) | 33 (44.6%) | 8 (9.9%) | 47 (58%) | |||||||
| CD163 | |||||||||||||||
| High | 2 (3.4%) | 26 (44.1%) | 0.7 | 19 (25.7%) | 10 (13.5%) | 0.03 & | 14 (18.9%) | 15 (20.2%) | 0.0004 ° | ||||||
| Low | 3 (5.1%) | 28 (47.4%) | 18 (24.3%) | 27 (36.5%) | 5 (6.7%) | 40 (54%) | |||||||||
| MECA-79 | |||||||||||||||
| High | 3 (5.1%) | 2 (3.4%) | 0.8 | 2 (3.4%) | 3 (5.1%) | 0.6 | |||||||||
| Low | 30 (50.8%) | 24 (40.7%) | 16 (27.1%) | 38 (64.4%) | |||||||||||
| CD34 | |||||||||||||||
| High | 16 (21.6%) | 21 (28.4%) | 0.0005 + | ||||||||||||
| Low | 3 (4%) | 34 (46%) | |||||||||||||
Fisher’s exact test p values: * 0.02, § <0.0001, £ 0.001, & 0.05, ° 0.0007, + 0.0006. High = scores 2–3 and No = scores 0–1 for CD8, CD163, and CD20. Yes = presence, No = absence for PD-L1. High/Low corresponds to the median as the cut off for CD34 and MECA-79.