Figure 4.

Cardiomyocyte-specific YAP depletion activates TLR genes expression. (A). Genome browser view showing chromatin immunoprecipitation and high throughput sequencing (ChIP-seq) of TEAD1 occupancy near the transcriptional start site (TSS) or gene body of the TLR genes. E12.5 fetal heart and adult hearts were used for TEAD1^fb ChIP-seq. ChIP-seq data from two biological replicates are sown. (B). qRT-PCR measurement of cardiac TLR genes. Gene expression level was normalized to Gapdh. n = 4. Student t-test, *, p < 0.05.