Fig. 6.

Effect of a animal models’ characteristics, b type of fractured bone, c time of collection healing bones, d type of NSAID, and e age of the animals on biomechanical bending measurements (stiffness) after administration of NSAID compared to the administration of a control vehicle. The columns indicate the effect estimate with the 95% confidence interval of the subgroups. SMD, standard mean difference–Hedges’ g mean. NM, not mentioned; NS-COX, non-selective-cyclooxygenase; COX2, selective-cyclooxygenase 2 inhibitor