Table 2.
A summary of granulomatous conditions other than sarcoidosis.
| General Categories | Specific Conditions |
|---|---|
| Infections | |
| Mycobacteria | Tuberculosis |
| Non-tuberculous mycobacteria | |
| Fungi | Cryptococcus |
| Histoplasmosis | |
| Blastomycosis | |
| Coccidioidomycosis | |
| Other infections | Mycoplasma |
| Pneumocystis jiroveci | |
| Brucellosis | |
| Toxoplasmosis | |
| Leishmaniasis | |
| Schistosomiasis | |
| Bartonella | |
| Mononucleosis (Epstein Barr virus) | |
| Cytomegalovirus | |
| Coxiella burnetii (Q fever) | |
| Treponema (syphilis, yaws) | |
| Environmental and occupational exposures | |
| Hypersensitivity pneumonitis | |
| Pneumoconioses | Beryllium (chronic beryllium disease) |
| Titanium | |
| Aluminum | |
| Malignancies | Lymphoma |
| Sarcoidosis-like reaction of malignancy | |
| Vasculitidies/Connective tissue diseases | Granulomatosis with polyangiitis |
| Rheumatoid nodules | |
| Localized granulomatous reactions to foreign substances | Lung aspiration |
| Foreign body reactions | |
| Drug-induced sarcoidosis-like reactions (DISRs) | Highly active retroviral therapy (HAART) |
| Immune checkpoint inhibitors | |
| Tumor necrosis alpha antagonists | |
| Interferon | |
| Diffuse granulomatous reactions from an autoimmune inflammatory syndrome induced by adjuvants | |
| Granulomatous lesions of unknown significance (GLUS syndrome) | |
| Granulomatous interstitial lung disease (GLILD) related to common variable immunodeficiency (CVID) | |
| Necrotizing sarcoid granulomatosis | |
| Blau syndrome | |
| Orofacial granulomatosis | |
| Crohn’s disease | |
| Primary biliary cirrhosis | |