Figure 4.

Summary of the functional differences between cannabinoid CB1 and CB2 receptors in pathological cardiac hypertrophy (A), cardiac fibrosis (B), antipsychotic cardiotoxicity (C), and anti-tumor drug cardiotoxicity (D). The 2-AG is depicted as a representative endogenous ligand of cannabinoid receptors. ↓ indicates inhibition and ↑ indicates promotion.