20 nm |
10 to 100 μg/mL |
CRL-2310 |
Dose-dependent effect in cell viability reduction. Viability of 98.76% after treatment with 10 μg/mL |
[78] |
10, 30 and 60 nm CIT, PEG, BSA |
0 to 100 μg/mL |
HaCaT |
Alterations in metabolism and energy production related to ROS increase. |
[57] |
4.7 and 42 nm |
5 to 2000 μg/mL |
NHDF |
ROS increase, reduction of cell viability dose and size-dependent. |
[79] |
13, 33 and 46 nm tannic acid |
1 to 10 μg/mL |
291.03C |
Dose-dependent reduction in cell viability. Up regulation of TNF α |
[80] |
30 and 50 nm tannic acid and sodium borohydride |
5 to 100 μg/mL |
A431 |
Dose-dependent decrease of metabolic activity. Up regulation of TNF α |
[82] |
15.9 nm |
12.1 μg/mL |
A549 |
Modification in gene expression, increase in ROS production |
[83] |
15 nm |
0 to 50 μg/mL |
A549 |
Reduction in cell viability, increase in ROS dose dependent |
[84] |
10, 40 and 75 nm PVP, CIT |
5 to 50 μg/mL |
BEAS 2B |
Toxicity only at 20 and 50 μg/mL of 10 nm AgNP, damage in DNA. |
[85] |
20 nm |
1.95 μg/106 cells |
C3A |
Reduction in viability and cell function. Increase in IL-8 and TNF α |
[86] |
21.8 nm |
0 to 1600 μg/mL |
HepG2 |
Increase ROS production in dose dependent manner. Reduction of cell viability. |
[87] |
30 nm CIT, PEG |
0 to 50 μg/mL |
HepG2 |
Changes in expression of genes related to apoptosis and cell cycle. |
[88] |
200 nm |
0 to 100 μg/mL |
Caco 2 |
Significant toxic effects only at 100 μg/mL. Increase in IL-8 production. |
[89] |
20 and 40 nm peptide coated |
5 to 100 μg/mL |
Caco 2 |
Reduction of cell viability, increase in ROS, dose and size-dependent. |
[90] |