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. 2021 Jun 22;13(13):3110. doi: 10.3390/cancers13133110

Table 2.

Model development and multivariable regression coefficients after shrinkage.

Demographic Model Geriatric Model
Predictors Beta a Beta a
Cohort model estimates
Intercept −6.64 −2.64
Age (for every 10 years) 0.14 0.04
Male gender 0.26 0.32
BMI, kg/m2
History of abdominal surgery
Cardiac comorbidity
COPD/asthma/emphysema 0.27 0.34
Previous PE or DVT b 0.37 0.35
ASA score 0.2 0.02
Rectal tumour 0.03 0.12
Tumour stage *
Reported falls *
Risk for malnutrition *
Previous delirium * 0.33
Self-reported cognitive impairment * 0.09
Self-reported need for ADL assistance * 0.16
Mobility aid * 0.43
Polypharmacy (≥5) * 0.35
Model performance (AUC)
Model after bootstrapping 0.648 0.687
Optimism corrected model 0.623 0.650

a Regression coefficient after shrinkage using LASSO. – candidate predictor was not selected after shrinkage. * candidate predictor was not used in model development. b PE, Pulmonary Embolism; DVT, Deep Venous Thrombosis.