Table A3.
Comparison of Three Preoperative Risk Prediction Models
| Model Name | GerCRC | ACS-NSQIP Universal Model | CR-BHOM |
|---|---|---|---|
| Year | 2019 | 2013 [19] | 2011 [48] |
| Population | CRC surgery (Mean age 77) |
CR surgery (Mean age 61) |
CRC surgery (Mean age 74) |
| Definition Severe | Any complication leading to death, ICU admission >2 days, reintervention, or a hospital stay >14 days | Deep wound infection, wound disruption, CVA, MI, cardiac arrest, PE, ventilator dependence, AKI, major bleeding, sepsis | Anastomotic leakage, abscess, bleeding or bowel obstruction (not including mortality) |
| Complications | |||
| No. Predictors | 8 | 15 | 5 |
| Predictors | Gender, COPD/asthma/emphysema, Previous PE or DVT, rectal cancer, mobility aid, previous delirium, need for ADL assistance, polypharmacy | Age, tumour stage, COPD, dyspnoea, BMI, functional dependency, creatinine, albumin, PT time, sepsis, operative urgency, disseminated cancer, indication for surgery, surgical extent, wound class | Age, urea, sodium, albumin, operative urgency |
| Development AUC | 0.69 (0.65 #) | 0.72 | 0.70 |
| External AUC | none | none | 0.66 * |
| External calibration | none | none | Poor-fit * |
# Optimism corrected model. * Observational study across 182 octogenarians with malignant and nonmalignant indications for colorectal surgery. Complications defined as Clavian Dindo Grade II or higher. PE, pulmonary embolism; DVT, deep venous thrombosis; CVA, cerebral vascular accident; BMI, body mass index; PT, prothrombin time; AKI, acute kidney injury; MI, myocardial infarction.