HPV	Human Papillomavirus
RT	Radiation therapy
5-FU	Fluorouracil
mAb	Monoclonal antibody
PD-1	Programmed death receptor-1
RTOG	Radiation Therapy Oncology Group
NEDD8	Neural precursor cell expressed, developmentally-downregulated 8
UBA3	Ubiquitin-like modifier activating enzyme 3
APPBP1	NEDD8 activating enzyme E1 regulatory subunit
NAE	NEDD8 activating enzyme
UBC12	NEDD8 conjugating enzyme Ubc12
UBE2F	NEDD8 conjugating enzyme 2
RBX1	RING-box protein 1
RBX2	RING-box protein 2
COP9	Constitutive photomorphogenesis 9
CRL	Cullin RING ligase
CAND1	Cullin-associated NEDD8-dissociated protein 1
p21	Cyclin-dependent kinase inhibitor 1
p27	Cyclin-dependent kinase inhibitor 1b
Wee1	WEE1 G2 checkpoint kinase
RING	Really interesting new gene
Ub	Ubiquitin
PEV	Pevonedistat
CDT1	Chromatin licensing and DNA replication factor 1
PI-FACS	Propidium Iodide-fluorescent activated cell sorting
AML	Acute myeloid leukemia
MM	Multiple myeloma
HNSCC	Head and neck squamous cell carcinoma
NOXA	Phorbol-12-myristate-13-acetate-induced protein 1
BIM	Bcl-2-like protein 11
BH3	Bcl-2 homology 3 domain
TRAIL	Tumor necrosis factor-related apoptosis-inducing ligand
CDT2	Denticleless protein homolog
Gy	Gray (unit of radiation)
Chk1	Checkpoint kinase 1
Chk2	Checkpoint kinase 2
γH2AX	Gamma H2A histone family member X
PR	Partial response
AUC6	target area under the concentration-time curve of 6 mg/mL * min
ORR	Overall response rate
TAS	TAS4464
DCN1	Defective in Cullin NEDDylation 1
IC50	Half maximal inhibitory concentration