Table 2.

RegiSCAR score system. Table modified from Kardaun et al. [11,12].

Score	−1	0	1	2	Min	Max
Fever ≥ 38.5 °C	No/U	Yes			−1	0
Lymphadenopathy		No/U	Yes		0	1
Eosinophilia Eosinophils Eosinophils, if leukocytes < 4000			700–1499/μL 10–19.9%	≥1500/μL ≥20%	0	2
Atypical lymphocytes		No/U	Yes		0	1
Skin involvement Rash extent (>50% BSA) Rash suggesting DRESS Biopsy suggesting DRESS	No No	No/U U Yes/U	Yes Yes		−2	2
Organ involvement * Liver, kidney, lung, muscle/heart, pancreas, other organ (s)		No/U	Yes		0	2
Resolution ≥ 15 days	No/U	Yes			−1	0
Evaluation other potential causes ANA, blood culture, serology for HVA/HBV/HCV, C./M. Pneumoniae, other serology/PCR if none are positive and ≥3 above negative			Yes		0	1
TOTAL SCORE					−4	9

U = unknown/unclassifiable; BSA = body surface area; PCR = polymerase chain reaction; C./M. = Chlamydia/Mycoplasma. * after exclusion of other explanations: 1 = 1 organ; 2 = ≥2 organs. Final score: <2 = no case; 2–3 = possible case; 4–5 = probable case; >5 = definite case.