Table 1.
Correlation of CTC status to clinical parameters of breast cancer, NSCLC and melanoma patients.
| Breast Cancer | CTC | Lung Cancer | CTC | Melanoma | CTC | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Negative | Positive | Negative | Positive | Negative | Positive | ||||||||||||
| Total n | 14 | 7 | 7 | Total n | 18 | 9 | 9 | Total n | 11 | 7 | 4 | ||||||
| % | % | p | % | % | p | % | % | p | |||||||||
| Survival | 0.155 | Survival | 0.501 | Survival | 0.049 | ||||||||||||
| Alive | 5 | 20.0 | 80.0 | Alive | 4 | 50.0 | 50.0 | Alive | 6 | 100.0 | 0.0 | ||||||
| Dead | 9 | 66.7 | 33.3 | Dead | 14 | 57.1 | 42.9 | Dead | 5 | 20.0 | 80.0 | ||||||
| ER | 8 | 37.5 | 62.5 | 0.486 | BRAF | 0 | - | - | - | BRAF | 8 | 50.0 | 50.0 | - | |||
| PR | 6 | 33.3 | 66.7 | 0.486 | EGFR | 1 | 0.0 | 100.0 | - | PD-L1 | 3 | 66.7 | 33.3 | - | |||
| HER2 | 10 | 40.0 | 60.0 | 0.409 | NRAS | 3 | 66.7 | 33.3 | - | ||||||||
| BRCA1 | 2 | 100.0 | 0.0 | - | |||||||||||||
| Metastases | Metastases | Metastases | |||||||||||||||
| Bone | 10 | 0.999 | Bone | 18 | 0.999 | Bone | 6 | 0.206 | |||||||||
| No | 5 | 60.0 | 40.0 | No | 17 | 55.6 | 44.4 | No | 2 | 0.0 | 100.0 | ||||||
| Yes | 5 | 40.0 | 60.0 | Yes | 1 | 0.0 | 100.0 | Yes | 4 | 75.0 | 25.0 | ||||||
| Liver | 9 | 0.999 | Liver | 18 | 0.999 | Liver | 8 | 0.003 | |||||||||
| No | 7 | 42.9 | 57.1 | No | 17 | 55.6 | 44.4 | No | 3 | 0.0 | 100.0 | ||||||
| Yes | 2 | 50.0 | 50.0 | Yes | 1 | 100.0 | 0.0 | Yes | 5 | 100.0 | 0.0 | ||||||
| Lung | 10 | 0.999 | Lung | 18 | 0.999 | Lung | 8 | - | |||||||||
| No | 5 | 40.0 | 60.0 | No | 17 | 55.6 | 44.4 | No | 0 | - | - | ||||||
| Yes | 5 | 40.0 | 60.0 | Yes | 1 | 100.0 | 0.0 | Yes | 8 | 50.0 | 50.0 | ||||||
| Lymph node | 11 | 0.437 | Lymph node | 18 | 0.999 | Lymph node | 8 | - | |||||||||
| No | 7 | 42.9 | 57.1 | No | 10 | 54.5 | 45.5 | No | 0 | ||||||||
| Yes | 4 | 75.0 | 25.0 | Yes | 8 | 62.5 | 37.5 | Yes | 8 | 62.5 | 37.5 | ||||||
| Other organ | 9 | 0.487 | Other organ | 18 | 0.999 | Other organ | 9 | 0.999 | |||||||||
| No | 5 | 40.0 | 60.0 | No | 15 | 50.0 | 50.0 | No | 1 | 100.0 | 0.0 | ||||||
| Yes | 4 | 75.0 | 25.0 | Yes | 3 | 100.0 | 0.0 | Yes | 8 | 50.0 | 50.0 | ||||||
| Oligo brain | 9 | 0.999 | Oligo brain | 18 | 0.394 | Oligo brain | 11 | 0.999 | |||||||||
| No | 7 | 42.9 | 57.1 | No | 3 | 54.5 | 45.5 | No | 10 | 60.0 | 40.0 | ||||||
| Yes | 2 | 60.0 | 40.0 | Yes | 15 | 47.0 | 53.0 | Yes | 1 | 100.0 | 0.0 | ||||||