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. 2021 Jul 1;10(13):2968. doi: 10.3390/jcm10132968

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Schematic representation of the different mechanisms involved in the development of post-STEMI LVR. ECM: extracellular matrix; iLVEDV: indexed left ventricular end-diastolic volume; LVR: left ventricular remodeling; STEMI: ST elevation myocardial infarction; miRs: micro-RNAs; IL: interleukin; IFN-γ: interferon-γ; TNF-α: tumor necrosis factor-α; Ly6c: lymphocyte 6 cytotoxic; TGF-β: tumor growth factor-β; MMPs: metalloproteinases; TIMPs: tissue inhibitor of metalloproteinases. ↑ indicates an increase; ↓ indicates a decrease.