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. 2021 Jul 1;10(13):2968. doi: 10.3390/jcm10132968

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Principal effects of pharmacological therapies and mechanical interventions on pathophysiological determinants of post-STEMI LVR. LVR: left ventricular remodeling; STEMI: ST elevation myocardial infarction; RAAS: renin angiotensin aldosterone system; SAC/VAL: sacubitril/valsartan; PCSK9: proprotein convertase subtilisin/kexin type 9; Gp IIb IIIa; glycoprotein IIb IIIa; RIPer-C: remote ischemic perconditioning; RIPost-C: remote ischemic post-conditioning; miRs: micro-RNAs. ↑ indicates an increase; ↓ indicates a decrease.