Figure 2.
Principal effects of pharmacological therapies and mechanical interventions on pathophysiological determinants of post-STEMI LVR. LVR: left ventricular remodeling; STEMI: ST elevation myocardial infarction; RAAS: renin angiotensin aldosterone system; SAC/VAL: sacubitril/valsartan; PCSK9: proprotein convertase subtilisin/kexin type 9; Gp IIb IIIa; glycoprotein IIb IIIa; RIPer-C: remote ischemic perconditioning; RIPost-C: remote ischemic post-conditioning; miRs: micro-RNAs. ↑ indicates an increase; ↓ indicates a decrease.