TABLE 2.
Levels of D‐dimer and thrombin generation parameters at baseline
| Parameter |
All patients N = 215 |
Provoked VT patients N = 106 | Unprovoked VT patients N = 106 |
Controls N = 358 |
Mean difference (all patients‐controls) (95% CI) |
|---|---|---|---|---|---|
| HemosIL D‐dimer, ng/mL | |||||
| Mean (95% CI) | 1260 (1097‐1423) | 1240 (1004‐1475) | 1303 (1069‐1538) | 818 (668‐968) | 442 (221 to 663) |
| Thrombinoscope TG (CAT) | |||||
| ETP, nM.min, mean (95% CI) | 1401.8 (1332‐1471.6) | 1339.1 (1285.9‐1392.3) | 1409.8 (1354‐1465.6) | 1163.3(1132‐1194.6) | 238.4 (171.1 to 305.8) |
| Peak, nM, mean (95% CI) | 129.4 (119.5‐139.4) | 121.5 (114‐129.1) | 129.5 (122.2‐136.8) | 101.3 (97.3‐105.2) | 28.2 (18.9 to 37.4) |
| Time‐to‐peak, min, mean (95% CI) | 15.2 (14.9‐15.5) | 15.4 (15‐15.8) | 15 (14.6‐15.5) | 15.7 (15.4‐15.9) | −0.5 (−0.9 to −0.1) |
| Lag time, min, mean (95% CI) | 8.8 (8.5‐9) | 8.8 (8.5‐9.2) | 8.6 (8.3‐9) | 8.8 (8.6‐9) | −0.0 (−0.4 to 0.3) |
| Velocity index, mean (95% CI) | 22.5 (19.4‐25.6) | 20.4 (18.2‐22.5) | 22 (20‐23.9) | 16.4 (15.3‐17.5) | 6.1 (2.8 to 9.4) |
Abbreviations: CAT, calibrated automated thrombography; CI, confidence interval; ETP, endogenous thrombin potential.