Table 1.
Diagnostic performance of liquid biopsy in brain tumors.
| Group/Markers | Significance | Study |
|---|---|---|
| Molecular biomarkers | ||
| O-6 methylguanine-DNA methyltransferase | Prognostic and predictive biomarker | [7,8] |
| Epidermal growth factor receptor | Prognostic biomarker | [9,10] |
| Isocitrate dehydrogenase | Prognostic biomarker | [11,12] |
| Glial fibrillary acidic protein | Prognostic biomarker | [13,14] |
| Telomerase reverse transcriptase (TERT) | Prognostic biomarker | [15,16] |
| Loss of heterozygosity (LOH) | Prognostic and predictive biomarker | [17,18] |
| Tumor protein 53 (TP53) | Prognostic biomarker | [19,20] |
| Circulating tumor cells | Prognostic biomarker | [21,22] |
| Circulating free DNA | Diagnosis and monitoring response to treatment | [19,23] |
| Circulating cell-free microRNAs | Diagnosis and monitoring response to treatment | [24,25] |
| Circulating extracellular vesicles | Predictive and monitoring response to treatment | [26,27] |
| Circulating proteins | Diagnosis and monitoring response to treatment |