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. 2021 Jun 23;22(13):6726. doi: 10.3390/ijms22136726

Figure 1.

Figure 1

Analysis of FRMD5 expression in human thyroid tissues. (A) Boxplot of FRMD5 gene expression in papillary thyroid cancer (PTC) sections using The Cancer Genome Atlas (TCGA) databases and the Genotype Tissue Expression (GTEx) (tumor (T) vs. non-cancerous tissue (N)). (B) Boxplot of FRMD5 gene expression in BRAF-like and RAS-like PTC subtypes vs. non-cancerous tissues. (C) Boxplot of FRMD5 gene expression in PTC bearing the wild-type (BRAF-wt) and mutated BRAF (BRAF V600E) gene determined by microarray analysis. (D) Western blot analysis of FRMD5 protein expression in BRAF-wt and BRAF V600E PTCs and non-tumoral (NT) tissues. β-actin serves as a loading control. Data are presented as mean ± SD.* p < 0.05; *** p < 0.0001.