Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Gq/11-coupled mAChRs evoke [Ca2+]i increases in T cells. Gq/11-coupled M3 and/or M5 mAChR activation results in IP3-mediated Ca2+ release from the endoplasmic reticulum followed by extracellular Ca2+ influx through CRACs, which mediate repetitive [Ca2+]i oscillations in T cells. The increase in [Ca2+]i is required to enhance c-fos gene expression.
