Figure 2.

Workflow of typical prostate cancer AI CAD systems. Systems are categorized as ROI Classification (ROI-C), Lesion Localization and Classification (LL&C), or Patient Classification (PAT-C). Blue indicates mpMRI input, yellow indicates manual processes, white indicates automated processes, and green indicates intermediate or final outputs. ROI = region of interest. CNN = convolutional neural network. ML = machine learning. ML* here refers to ML algorithms exclusive of CNNs, such as support vector machines, random forest, logistic regression, and artificial neural networks.